Another naturally circulating hormone found in humans. First researched at the University of Barcelona it was found to induce body-fat loss while preserving protein stores. This is important because most diets that induce fat loss are also responsible for protein loss as well. The ultimate goal of any diet agent is to preserve protein. Researchers are speculating that OE does so by lowering the body's body fat set point which allows the body to maintain a reduced body fat without experiencing a hormonal response aimed at regaining lost body fat. OE is currently licensed to Manhattan Pharmaceuticals and Phase I trials were conducted in Switzerland. The results were promising. They showed OE to lead to some weight loss after just 7 days of dosing and most importantly in the treatment groups this weight loss was maintained for 3 further weeks after treatment had stopped. A Phase IIa trial of 100 patients are in motion.
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