Friday, February 15, 2008

Growth Hormone / 7 Keto DHEA synergy

Growth hormone2The decline of our fundamental hormones is directly associated with certain aging signs like shrinkling of the skin, graying of the hair, decreased energy and sexual function, increased body fat, heart disease, weak and brittle bones, and much more. The good news is that DHEA and growth hormone, when properly supplemented, can significantly relieve these physical signs and restore energy levels, bone strength, hair color, more youthful appearing skin, and for most people, an increased, youthful muscle mass while simultaneously reducing body fat.  As I mentioned earlier, DHEA enhances insulin-like growth factor -1 (IGF-1) release. IGF-1 (formerly called "Somatomedin C") is the "hidden anabolic power behind the throne" of growth hormone (GH).


Human growth hormone is secreted by the anterior pituitary gland. In 1985, biosynthetic human growth hormone replaced pituitary-derived (the cadavers of dead babies) human growth hormone for therapeutic use in the U.S. and elsewhere. Biosynthetic human growth hormone, also referred to as recombinant human growth hormone, somatropin and is abbreviated as rhGH.


Growth hormone can generally be described as anabolic (building up). Like most other protein hormones GH acts by interacting with a specific receptor on the surface of cells. Although height growth is the best known effect of GH, it serves many other metabolic functions as well.


GH increases calcium retention, and strengthens and increases the mineralization of bone. It increases muscle mass through the creation of new muscle cells (which differs from hypertrophy), and it also promotes lipolysis, which results in the reduction of adipose tissue (body fat). As well, it increases protein synthesis and stimulates the growth of all internal organs excluding the brain.


Deficiency of GH produces significantly different problems at various ages. In children, growth failure and short stature are the major manifestations of GH deficiency. In adults the effects of deficiency are more subtle, and may include deficiencies of strength, energy, and bone mass, as well as increased cardiovascular risk.


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